One victim was reported by the television station as a 13-year-old girl.
A student interviewed by WTTV said the shooter entered a science class and the teacher swatted a gun away from the shooter.
After the IN attack, students were bused to the Noblesville High School gym, where hundreds of parents and other family members arrived to retrieve them.
Police say a student at Noblesville West Middle School is responsible for shooting a teacher and classmate Friday morning. "We have not received any information that this has been anything other than a communicated threat", Jowitt said.
The shooting at the 1,350-student school happened a day before everyone was headed for a three-day Memorial Day holiday weekend.
One student told News 8 that he heard several shots fired but did not know if they were fired inside or outside of the building.
Indiana State Police Superintendent Doug Carter said he had briefed Gov. Eric Holcomb as Holcomb returned from Europe.
Another student was being treated at Riverview Health in Noblesville with a fractured ankle. The school is on lockdown.More news: Sensex falls over 100 pts, Nifty tests 10650; RCom rallies 18%
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Lauren Hogg, a student at Marjory Stoneman Douglas High School where 17 people were shot and killed earlier this year, slammed Mike Pence on Friday after the vice president offered his prayers for the victims in Friday's shooting in Indiana.
Reports of a school shooter led to Noblesville West Middle School being locked down Friday morning.
Helicopter footage showed dozens of police officers milling around the school. "Suspect in custody All students are being taken to the Noblesville High School, parents are asked to pick up there".
Vice President Mike Pence, the former governor of IN, tweeted about the incident.
Police from several local communities, as well as the Federal Bureau of Investigation and ATF, responded to the school, located about 30 miles north of Indianapolis.
NOBLESVILLE, IN - MAY 25: Substitute teacher Joanie Lynne, (L) consoles instructional assistant Paige Rose outside Noblesville West Middle School after a shooting at the school on May 25, 2018 in Noblesville, Indiana.
The shooting comes a week after 10 people were killed at a school in Santa Fe, Texas. The officer shot and wounded the suspect, who was arrested before anyone else could be injured.
Jacob Long, an eighth-grader, described a chaotic scene in his medical detectives class with students crying and teachers taking off their belts to lash doors closed.