Thomas Markle Sr, 73, is reportedly undergoing heart surgery on Wednesday, according to the United States celebrity website TMZ through which, after months of silence, the retired TV lighting director now appears to communicate.
He told celebrity website TMZ that doctors would clear any blockage, fix damage and "put a stent where it is needed".
However, much of the carefully-planned and choreographed build-up to the ceremony has been overshadowed by confusion over whether Markle's father would attend.
Sky News reported that Ragland received VIP treatment.
Meghan Markle's father, who has been at the centre of a storm of controversy over the past few days, is recovering in hospital following a successful heart operation.
Mr Markle told the TMZ site his daughter harbours no ill feelings towards him over the alleged collusion with the paparazzi agency, and he said about the Queen's interest in events: "I don't think the Queen is thinking about what I'm doing". Royal commentators have speculated Ragland will now walk her daughter down the aisle instead.
"It must be heartbreaking for them, because her father can't come because he is in poor health", said 46-year-old Maria Scott who had traveled from Newcastle to camp out in Windsor to get a glimpse of the couple on Saturday. Prince Harry's godson Jasper Dyer and Ivy Mulroney's brothers, twins Brian and John Mulroney, 7 are the page boys.
Prince Harry's press office said it had no additional comment beyond a statement made two days ago calling for "understanding and respect" for Markle's father, Thomas, "in this hard situation".More news: European Union to Move Friday to Block US Sanctions on Iran
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The palace could not be reached for further comment.
Samantha Markle is no stranger to controversy, especially since it's been revealed that it was she who was responsible for Thomas Markle's recent revelation of staging paparazzi photos to sell to the press.
"It must be really upsetting but I'm sure her mum will do a fine job", Scott told Reuters.
Truthfully, we won't know for sure whether Thomas will attend the royal wedding or not until the actual royal wedding. "They photograph you as unflattering ways as can be", she said.
Staging the photos was meant to counter the way he had been "so unfairly presented in the media as being sort of shabby".
In the statement released by Kensington Palace, Prince Harry's official residence, Markle thanked "everyone who has offered generous messages of support".
Apart from a book she has been flogging with the title The Diary of Princess Pushy's Sister she has spent most of the last two years wheeling herself out to provide commentary on Meghan Markle and her curious family.
The loved-up pair will leave their Royal Wedding at Windsor Castle on Saturday with fancy new names as a gift from the Queen.