A week after City surrendered a 2-0 lead to lose 3-2 to United and squander the chance to wrap up the title in ideal style against their arch-rivals, it was relegation-bound West Brom who served it up on a plate.
By completing the job after 33 games, City have emulated the achievement of United, who secured the crown with the same number of matches to spare in 2001.
Guardiola's side also set a new record for most consecutive victories with 18 wins in a row earlier in the season and the City boss said the players showed their quality to claim the title.
Defeat for Spurs handed Chelsea a glimmer of hope in the fight for Champions League places after it came from 2-0 down to beat Southampton 3-2, but Liverpool strengthened its position in the top four as Mohamed Salah scored his 40th goal of the season in a routine 3-0 win over Bournemouth.
Guardiola's response was to spend a club record £57 million (US$80.3 million, RM315 million) on Aymeric Laporte from Athletic Bilbao in January, taking his spending to an eye-watering £448 million on 16 players since arriving.
But Guardiola believes the 1-0 win at Stamford Bridge was a pivotal moment when Kevin De Bruyne's goal saw them pick up a deserved three points after dominating against the defending champions.
West Brom had lost eight of their previous nine games and last won on Jan 13.More news: 'Big things can get done in Canada,' Trudeau tells business leaders
More news: Sunday marks five years since Boston Marathon bombing
More news: U.S. still 'locked and loaded' for new chemical attacks
Manchester United hold the current record of Premier League winning margin of 18 points and City and breach this feat too.
"I've never been able to retain the title so I want to see if this team has got it in them to carry on and be even more successful".
"I had a feeling when I woke up this morning but it's a different experience when you're waiting for a team to lose".
"He unlocks everything but when you think about it he did much, much better than last season and that was important".
"Pep's beliefs determine how his team play, the way I wanted my teams to play, so put me down as one of his admirers".
It was a far cry from his trophy-less first season with City and Kompany said Guardiola's tenacious attitude led them to the summit.
It is the team's first league title since 2014. "The Premier League is the constant - every day, every day, every day - and we were there every day".