Pakistan had been a no-go zone for global teams since a 2009 terrorist attack on the Sri Lankan team bus which killed eight people and left seven visiting players injured.
Pakistan Cricket Board (PCB) chairman Najam Sethi said the West Indies have confirmed the series.
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Earlier both Boards were in talk with each other but West Indies board kept delaying the deal due to some security reasons. "The idea wasn't to make money, it was to bring cricket back, so this is a step in that direction".
Two eliminators of Pakistan Super League 2018 will be played in Lahore on March 20 and 21 respectively.
International Cricket Council's security consultant Reg Dickason will visit Karachi during the PSL final to assess security arrangement for the Twenty20 series.
Talking to a private news channel, Bazid, who represented Pakistan in one Test and five ODIs between 2004 and 2008, said that the third edition of PSL shows that we have also improved our standards of fielding.