Newhall Ranch Road is also closed between the 126 and Rye Canyon Road, the city reported.
According to an ABC News affiliate, a two-alarm fire that broke out in the Santa Clarita, California, region and has shut down both directions of traffic on the 5 Freeway going through metro Los Angeles.
The FEMA Regional Administrator determined Tuesday that "the Rye Fire threatened such destruction as would constitute a major disaster", the news release stated.
As of 3:20 p.m., the Rye Fire has grown to 5,000 acres with 5 percent containment. Westridge High School, Rancho Pico Middle School and Oak Hills Elementary School were evacuated as well.
In addition, the Simi Valley Police Department announced that schools in the Simi Valley Unified School District will be closed Wednesday, Dec. 6.More news: Evacuations ordered in Bel Air as wildfire burns near the 405 freeway
More news: United States defense chief calls for deepening anti-terror cooperation with Pakistan
More news: Analyst's Rankings to Lookout: Occidental Petroleum Corporation (OXY), Globalstar, Inc. (GSAT)
The Creek Fire in the mountains above Sylmar has burned 11,000 acres and forced the closure of the 210 freeway and the interchange with the 118 freeway.
All classes starting at 5 p.m. or later at both campuses of College of the Canyons were canceled. No injuries were immediately reported.
Gusty winds kept firefighting aircraft grounded and may have also been the cause of a power outage that interrupted service to about 2,090 customers in the Santa Clarita area.
The Rye Fire burns in the Santa Clarita area on December 5, 2017. Parents will be able to meet with their children there, officials said.
According to reports, the 50-acre Skirball Fire was first reported at about early Wednesday morning on the east side of the northbound lanes across the freeway from Skirball Center Drive.